Flexible, Cost-Effective Manufacturing of CD19-CAR T Cells Using the G-Rex® System

This technical application poster, originally showcased at CAR TCR 2023, shares data demonstrating OmniaBio’s flexible and cost-effective manufacturing platform that can be tailored to accommodate specific client needs. The poster shows the integration of the CliniMACS® Plus (Miltenyi Biotec) for T cell isolation, G-Rex® (Wilson Wolf Manufacturing) for T cell activation and expansion, followed by washing using Lovo® Automated Cell Processing System (Fresenius Kabi), presenting a platform that can advance your CAR T cell therapy manufacturing path. The platform developed is a robust CAR T manufacturing process using unit operations, which is flexible, cost-effective, and has the potential to reduce the GMP footprint by eight-fold.

While CAR T therapies have shown remarkable success in oncology and they continue to be evaluated to address other devastating diseases, manufacturing remains a challenge. Selecting the optimal manufacturing platform often comes down to program specific requirements. Leveraging a development team with experience evaluating the performance of multiple CAR T manufacturing technology and approaches with the end in mind can help you select the right manufacturing platform upfront that will meet your manufacturing strategy goals streamlining your path to market.

Download this poster to learn about how we can help streamline your CAR T program journey.


About OmniaBio

As a dedicated cell and gene therapy CDMO, OmniaBio's vision is to manufacture a disease-free future. Headquartered in Ontario, Canada, our core values of collaborative partnership converge with deep industry experience and innovation using the latest technologies to drive the future of cell and gene therapy manufacturing.

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